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Regional pulmonary function in supine patients with mitral valve disease

Conference · · Radiology, v. 117, no. 1, pp. 99-104
OSTI ID:4142820
Supine tidal volume regional ventilation and perfusion images obtained using $sup 133$Xe and /sup 99m/Tc-MAA tracers in the posterior and lateral projections demonstrated several alterations in patients with mitral valve disease. Reversal of the gravitational perfusion gradient correlated with pulmonary venous and arterial hypertension; the supine studies reliably distinguished normal subjects from mitral patients. The reversed gradient was from posterior-base to anterior-apex. Focal defects were common and contributed to the reversed gradient in 50 percent of patients. Perfusion defects larger than those of ventilation, simulating emboli, occurred in 32 percent, particularly in the middle lobe and superior segment areas. Relative hypoventilation of the left lung was seen in 44 percent of these patients. (auth)
Research Organization:
Univ. of California, Los Angeles
NSA Number:
NSA-33-001067
OSTI ID:
4142820
Conference Information:
Journal Name: Radiology, v. 117, no. 1, pp. 99-104
Country of Publication:
United States
Language:
English