Scintigraphic definition of pulmonary embolism

Journal Article · Mon Feb 18 04:00:00 EDT 1974 · J. Amer. Med. Ass., v. 227, no. 7, pp. 753-756

DOI:https://doi.org/10.1001/jama.1974.03230200011002· OSTI ID:4327689

McNeil, B J; Holman, L; Adelstein, J

Pulmonary scintigrams were analyzed in conjunction with matched pulomnary angiograms for perfusion petterns, relation of perfusion to ventilation, and changes, with time, in the perfusion pattern. Eighty percent of the patients with lobar defects seen on scan and 30% with segmental or subsegmental defects had angiographic evidence of pulmonary embolism. Patients with lobar defects and pulmonary embolism had a lower incidence of findings on chest roentgenograms than did the other groups. Of the 20 patients with mismatched abnormalities of perfusion and ventilation, 19 had pulmonary emboli; none of the five patients with matched perfusion and ventilation had emboli. A rapidly changing perfusion pattern was found in ten patients with acute pulmonary embolism while a fixed pattern was found in five patients who did not have emboli. The data indicate that a large perfusion defect and a ventilation-perfuslon mismatch correlate strongly with pulmonary embolism. (auth)

• Research Organization: Harvard Medical School, Boston
• Sponsoring Organization: USDOE
• NSA Number: NSA-29-021286
• OSTI ID: 4327689
• Journal Information: J. Amer. Med. Ass., v. 227, no. 7, pp. 753-756, Journal Name: J. Amer. Med. Ass., v. 227, no. 7, pp. 753-756; ISSN JAMAA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*LUNGS-- SCINTISCANNING
DIAGNOSTIC TECHNIQUES
IRON HYDROXIDES
ISOMERIC NUCLEI
N48830* --Life Sciences--New Tracer Techniques--Other
PATIENTS
TECHNETIUM 99