Review of toxicology studies on cyanurate and its chlorinated derivatives

Journal Article · Sat Nov 01 04:00:00 EST 1986 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.8669287· OSTI ID:5555032

Hammond, B G; Barbee, S J; Inoue, T; Ishida, N; Levinskas, G J; Stevens, M W; Wheeler, A G; Cascieri, T

Chlorinated cyanurates are added to swimming pools as disinfectants. In the presence of water, these materials hydrolyze to yield cyanurate and hypochlorous acid. To evaluate the safety of exposure to these materials, a comprehensive testing program was undertaken. This review summarizes the results of acute subchronic tests on chlorinated isocyanurates. Findings from acute, subchronic, reproduction, metabolism, mutagenicity, and chronic/carcinogenicity tests on cyanurate are also summarized. Results from these tests indicate that chlorinated isocyanurates are safe for use in swimming pools.

• Research Organization: Monsanto Co., St. Louis, MO
• OSTI ID: 5555032
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 69; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

550201 -- Biochemistry-- Tracer Techniques
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AZINES
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY
BODY FLUIDS
CARBON 14 COMPOUNDS
CYANURATES
DISINFECTANTS
GERMICIDES
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
HYPOCHLOROUS ACID
INORGANIC ACIDS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
MATERIALS
MUTAGEN SCREENING
NATIONAL ORGANIZATIONS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
RABBITS
RATS
REPRODUCTION
RODENTS
SCREENING
SKIN
SURFACE WATERS
SWIMMING POOLS
TERATOGENESIS
TOXICITY
TRACER TECHNIQUES
TRIAZINES
URINE
US EPA
US ORGANIZATIONS
VERTEBRATES
WASTES