Effect of sodium meclofenamate on ultraviolet radiation induced carcinogenesis

Journal Article · Sun Jan 01 04:00:00 EST 1984 · J. Med. (Westbury, N.Y.); (United States)

OSTI ID:5547802

Ambrus, J L; Ambrus, C M; Pickren, J W; Klein, E

Sodium meclofenamate (Meclomen), an antiprostaglandin antileukotriene agent, was found in previous studies to protect primates against x-ray induced brain edema, esophagitis and cystitis. In the present study, it appeared to protect hairless mice against the carcinogenic effect of ultraviolet B-radiation.

• Research Organization: Roswell Park Memorial Institute, Buffalo, NY
• OSTI ID: 5547802
• Journal Information: J. Med. (Westbury, N.Y.); (United States), Journal Name: J. Med. (Westbury, N.Y.); (United States) Vol. 15:3; ISSN JNMDB
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
ANIMALS
ANTHRANILIC ACID
ANTIMETABOLITES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BRAIN
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
DISEASES
DRUGS
EDEMA
ELECTROMAGNETIC RADIATION
INJURIES
IONIZING RADIATIONS
MAMMALS
MICE
NEOPLASMS
NERVOUS SYSTEM
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
PROSTAGLANDINS
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RODENTS
SYMPTOMS
ULTRAVIOLET RADIATION
VERTEBRATES
X RADIATION