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Complications associated with preoperative radiation therapy and Iodine-125 brachytherapy for localized prostatic carcinoma

Journal Article · · Urology (Ridgewood, N.J.); (United States)
; ; ; ; ;

Twenty-five consecutive patients with localized adenocarcinoma of the prostate treated with 1,050 rad preoperative radiation therapy and Iodine-125 seed brachytherapy are reviewed. Significant long-term postoperative complications included radiation cystitis (12%), radiation proctitis (4%), genital and leg edema (12%), stress incontinence (8%), total incontinence (4%), and impotence (26%). Complications occurred in 75 per cent of patients who received additional postoperative radiation. Improved staging with CT scan, lymphangiography, and Chiba needle biopsy of any possibly abnormal lymph nodes provided excellent preoperative staging with only 1 patient (6%) upstaged at surgery to Stage D1.

Research Organization:
Department of Surgery, University of Kentucky Medical Center, Lexington
OSTI ID:
5545535
Journal Information:
Urology (Ridgewood, N.J.); (United States), Journal Name: Urology (Ridgewood, N.J.); (United States) Vol. 22:2; ISSN URGYA
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOPSY
BLADDER
BODY
BODY AREAS
CARCINOMAS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
EDEMA
ELECTRON CAPTURE RADIOISOTOPES
GLANDS
IMPLANTS
INFLAMMATION
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
LEGS
LIMBS
LYMPHATIC SYSTEM
MALE GENITALS
MALES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
PROSTATE
RADIATION EFFECTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SCINTISCANNING
SIDE EFFECTS
SYMPTOMS
THERAPY
TOMOGRAPHY
URINARY TRACT