Comparability and precision of serum PCB measurements

Journal Article · · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1985.10545886· OSTI ID:5525745

Lawton, R W; Brown, Jr, J F; Ross, M R; Feingold, J

The 95% prediction interval for single measurements of serum Aroclor reported by a reputable commercial analyst was found to be approximately +/-42%. The geometric mean serum PCB levels in a population of capacitor workers who had formerly had direct exposure to the commercial PCBs - Aroclors 1016, 1242, and 1254 - were found to be alternatively reportable as 1905 ppb minimum initial PCBs (as calculated from most persistent peaks present); 1093 ppb non-overlapping analytical Aroclor levels (as calculated by the conventional sum-of-the-peak-heights method); 303 ppb total PCBs actually present; or 19 ppb human PCB (as calculated by the NHMP procedure). The broad spread in reportable values was relatable to the PCB isomer distribution and clearance patterns in the occupationally exposed population.

• Research Organization: General Electric Research and Development Center, Schenectady, NY
• OSTI ID: 5525745
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 40:1; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
ACCURACY
AROMATICS
BLOOD SERUM
CAPACITORS
CHLORINATED AROMATIC HYDROCARBONS
CLEARANCE
COMPARATIVE EVALUATIONS
ELECTRICAL EQUIPMENT
EQUIPMENT
HALOGENATED AROMATIC HYDROCARBONS
MEASURING METHODS
OCCUPATIONAL EXPOSURE
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS