Echocardiographic abnormalities following cardiac radiation

Journal Article · Mon Apr 01 04:00:00 EST 1985 · J. Clin. Oncol.; (United States)

OSTI ID:5518519

Perrault, D J; Levy, M; Herman, J D; Burns, R J; Bar Shlomo, B Z; Druck, M N; Wu, W Q; McLaughlin, P R; Gilbert, B W

Five years or more after receiving cardiac radiation, 41 patients with Hodgkin's disease and seminoma in remission were subjected to echocardiography. The abnormalities detected included pericardial thickening in 70%, thickening of the aortic and/or mitral valves in 28%, right ventricular dilatation or hypokinesis in 39%, and left ventricular dysfunction in 39%. In the 23 patients treated by an upper mantle technique with shielding, the incidence of right ventricular abnormalities and valvular thickening was significantly lower than in patients treated with modified techniques. Although no symptoms were attributable to the observed abnormalities, longer follow-up time may reveal important functional implications.

• Research Organization: Princess Margaret Hospital, Toronto, Canada
• OSTI ID: 5518519
• Journal Information: J. Clin. Oncol.; (United States), Journal Name: J. Clin. Oncol.; (United States) Vol. 3:4; ISSN JCOND
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARDIOVASCULAR SYSTEM
DISEASES
GONADS
HEART
HODGKINS DISEASE
INJURIES
LYMPHOMAS
MALE GENITALS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
TESTES
THERAPY
ULTRASONOGRAPHY