Chromosome aberrations as a biological dosimeter in Thorotrast patients: dosimetric problems

Journal Article · Thu Feb 01 04:00:00 EST 1979 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(79)90151-8· OSTI ID:5511272

Kemmer, W; Steinstraesser, A; Muth, H

The results of chromosome aberration analyses in 68 Thorotrast patients are discussed. In all patients dicentric chromosome aberrations were found but the chromosome aberration rate neither corresponds with the calculated whole body activity or the estimated absorbed dose in the organs of the RHS nor with the radium-224-equivalent value calculated from the radon-220 activity measured in the expired air. From x-ray examinations and histologic studies of lymph nodes the conclusion is drawn that the microdose absorbed from one lymphocyte is not in relation to the mean absorbed RHS dose, calculated from biophysical measurements.

• Research Organization: Universitaet des Saarlandes, Homburg, Germany
• OSTI ID: 5511272
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 18:1; ISSN ENVRA
• Country of Publication: United States
• Language: English

Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560171* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE COMPOUNDS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CHALCOGENIDES
CHROMOSOMAL ABERRATIONS
CHROMOSOMES
COLLOIDS
CONTRAST MEDIA
DICENTRIC CHROMOSOMES
DISPERSIONS
DOSE-RESPONSE RELATIONSHIPS
DOSES
HISTOLOGY
LYMPH NODES
LYMPHATIC SYSTEM
MUTATIONS
OXIDES
OXYGEN COMPOUNDS
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIOCOLLOIDS
RADIOINDUCTION
RADIONUCLIDE KINETICS
RETICULOENDOTHELIAL SYSTEM
THORIUM COMPOUNDS
THORIUM OXIDES
THOROTRAST
TISSUES