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State of muscular coat of the stomach following local irradiation. [X rays; rats]

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5503601
Experiments were conducted on young albino rats exposed to local x radiation. A segment of the abdomen in the region of the stomach was irradiated. No signs of radiation sickness were observed in the irradiated animals. The reactive changes in the muscular coat of the stomach became marked on the 3d-7th postradiation day. There was also some change in biometric parameters of the muscular coat, as compared to the control. After 14 to 21 days, destructive changes in muscle tissue were observed. Fibrosis of the muscular coat and intermuscular connective tissue septa was rather distinct 50 to 75 days after radiation. As was the case at other times, the lesions to gastric muscles remained focal, but the most altered regions were adjacent to the submucosa. Sclerotic changes developed in the gastric wall 90 to 120 days after exposure to radiation. Complete recovery of the structure of the muscular coat of the stomach did not occur 180 to 240 days after irradiation. The obtained data indicate that local irradiation induces development of both reactive and destructive changes in cellular and noncellular components of muscle and connective tissues of the stomach. (ERB)
Research Organization:
Kalinin State Medical Inst., USSR
OSTI ID:
5503601
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:2; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABDOMEN
ACUTE EXPOSURE
ACUTE IRRADIATION
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BODY
BODY AREAS
DATA
DATA FORMS
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
DISEASES
EARLY RADIATION EFFECTS
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
FIBROSIS
GASTROINTESTINAL TRACT
INFORMATION
INJURIES
IONIZING RADIATIONS
IRRADIATION
ISOLATED VALUES
LOCAL IRRADIATION
MAMMALS
MORPHOLOGICAL CHANGES
MUSCLES
NECROSIS
NUMERICAL DATA
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RADIOINDUCTION
RATS
RECOVERY
RODENTS
STOMACH
ULTRASTRUCTURAL CHANGES
VERTEBRATES
X RADIATION