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Instantaneous radioiodination of rose bengal at room temperature and a cold-kit therefor. [DOE patent application]

Patent ·
OSTI ID:5503236
; ;

The disclosure relates to the radioiodination of rose bengal at room temperature and a cold-kit therefor. A purified rose bengal tablet is stirred into acidified ethanol at or near room temperature, until a suspension forms. Reductant-free /sup 125/I/sup -/ is added and the resulting mixture stands until the exchange label reaction occurs at room temperature. A solution of sterile isotonic phosphate buffer and sodium hydroxide is added and the final resulting mixture is sterilized by filtration.

Assignee:
TIC; ERA-05-022770; EDB-80-062148
Patent Number(s):
None
OSTI ID:
5503236
Country of Publication:
United States
Language:
English

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Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
ALCOHOLS
BETA DECAY RADIOISOTOPES
CARBOXYLIC ACIDS
CHEMICAL PREPARATION
CHEMISTRY
DAYS LIVING RADIOISOTOPES
DRUGS
DYES
ELECTRON CAPTURE RADIOISOTOPES
ETHANOL
HYDROXY ACIDS
HYDROXY COMPOUNDS
INDICATORS
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC IODINE COMPOUNDS
RADIOACTIVE MATERIALS
RADIOCHEMISTRY
RADIOISOTOPES
RADIOPHARMACEUTICALS
REAGENTS
ROSE BENGAL
SYNTHESIS