Influence of sex and dietary calcium on intestinal cadmium absorption in rats

Journal Article · Mon Jan 01 04:00:00 EST 1979 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1979.10667363· OSTI ID:5486654

Kello, D; Dekanic, D; Kostial, K

The influence of sex and dietary calcium on whole-body retention of orally administered /sup 115m/CdCl/sub 2/ has a half-life of 43 days, distinguishing it from /sup 115/Cd of half-life 2.3 days was studied in one-year-old control and gonadectomized male and female rats. Gonadectomy was performed at the age of four months. Each of the four experimental groups was divided into three subgroups that were fed rat food with a different calcium content (2.4, 0.7, and 0.3% Ca) throughout the experiment. Regardless of sex and gonadectomy the mean percent values of /sup 115m/Cd retention in the whole body decreased with increasing dietary calcium level. Male rate retained less cadmium than all other experimental groups of animals. These data clearly point out that sex and diet might influence the level of ingested cadmium in the body.

• Research Organization: Inst. for Medical Research and Occupational Health, Zagreb, Yugoslavia
• OSTI ID: 5486654
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 34:1; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH METALS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CADMIUM 115
CADMIUM CHLORIDES
CADMIUM COMPOUNDS
CADMIUM HALIDES
CADMIUM ISOTOPES
CALCIUM
CHLORIDES
CHLORINE COMPOUNDS
DAYS LIVING RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
FEMALES
GONADS
HALIDES
HALOGEN COMPOUNDS
INTERMEDIATE MASS NUCLEI
INTESTINAL ABSORPTION
ISOTOPES
MALES
MAMMALS
METALS
NUCLEI
NUTRIENTS
ORAL ADMINISTRATION
RADIOISOTOPES
RATS
RETENTION
RODENTS
SEX
UPTAKE
VERTEBRATES