Influence of sex and age on the biological half-life of cadmium in mice

Journal Article · Sun Feb 01 04:00:00 EST 1981 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287398109529975· OSTI ID:6336917

Taguchi, T ^[1]; Suzuki, S

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1. Kochi Medical School, Nangoku-shi, Japan

The influence of age on the whole-body biological half-life of /sup 109/Cd was studied in male mice following ip injection. The influence of sex on whole-body and organ retention was ascertained after sc injection. The whole-body biological half-life of /sup 109/Cd of the older mice was more than twice that of the younger mice, and that of the female mice was longer than that of the males. These differences demonstrate a biological difference between males and females with respect to whole-body half-life of /sup 109/Cd. The effects of age and sex on the biological half-life of Cd in mice are assessed quantitatively.

• OSTI ID: 6336917
• Journal Information: J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 7:2; ISSN JTEHD
• Country of Publication: United States
• Language: English

Related Subjects

560172 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL HALF-LIFE
CADMIUM 109
CADMIUM ISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
INTRAPERITONEAL INJECTION
ISOTOPES
MAMMALS
MICE
NUCLEI
RADIOISOTOPES
RADIONUCLIDE KINETICS
RETENTION
RODENTS
SEX DEPENDENCE
SUBCUTANEOUS INJECTION
VERTEBRATES
YEARS LIVING RADIOISOTOPES