Racial differences in red cell cation transport and their relationship to essential hypertension

Journal Article · Thu Jan 01 00:00:00 EST 1981 · Clin. Exp. Hypertens.; (United States)

DOI:https://doi.org/10.3109/10641968109033691· OSTI ID:5467221

Woods, K L; Beevers, D G; West, M J

Red cell cation transport has been studied in normotensive and essential hypertensive groups of white and black (West Indian) subjects. In vitro uptake of the potassium analogue 86Rb was measured during short-term incubation of erythrocytes in the presence and absence of ouabain. Sodium pump activity was significantly greater (p less than 0.0005) in white hypertensives than in white normotensives. No such difference was observed between black hypertensive and normotensives. 86Rb uptake was significantly lower in black than in white normotensive individuals; this racial differences was not due to a difference in sodium pump activity.

• Research Organization: Department of Therapeutics, Medical School, Birmingham University, UK
• OSTI ID: 5467221
• Journal Information: Clin. Exp. Hypertens.; (United States), Vol. 3:4
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
ERYTHROCYTES
BIOCHEMISTRY
HYPERTENSION
PATHOLOGY
RUBIDIUM 86
DIAGNOSTIC USES
BIOCHEMICAL REACTION KINETICS
BLACK AMERICANS
IN VITRO
SODIUM
UPTAKE
ALKALI METAL ISOTOPES
ALKALI METALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARDIOVASCULAR DISEASES
CHEMISTRY
DAYS LIVING RADIOISOTOPES
DISEASES
ELEMENTS
HUMAN POPULATIONS
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KINETICS
MATERIALS
METALS
MINORITY GROUPS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
POPULATIONS
RADIOISOTOPES
REACTION KINETICS
RUBIDIUM ISOTOPES
SYMPTOMS
USES
VASCULAR DISEASES
550201* - Biochemistry- Tracer Techniques
550301 - Cytology- Tracer Techniques
550901 - Pathology- Tracer Techniques