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Isolation of a protein kinase induced by herpes simplex virus type 1

Journal Article · · J. Virol.; (United States)
OSTI ID:5451630

Researchers have isolated a new cyclic AMP-independent protein kinase activity induced in HeLa cells by infection with herpes simplex virus type 1. Induction of the enzyme does not occur in cells treated with cycloheximide at the time of infection, or in cells infected with UV-inactivated herpes simplex virus type 1. The amount of enzyme induced in infected cells is dependent upon the multiplicity of infection. An enzyme with identical properties to the appearing in infected HeLa cells is also induced by herpes simplex virus type 1 in BHK cells.

OSTI ID:
5451630
Journal Information:
J. Virol.; (United States), Journal Name: J. Virol.; (United States) Vol. 38:1; ISSN JOVIA
Country of Publication:
United States
Language:
English