Process for the production of /sup 18/F-2-deoxy-2-fluoro-d-glucose

Patent ·

OSTI ID:5446138

Shiue, C Y; Salvadori, P A; Wolf, A P; Fowler, J S; MacGregor, R R

Process is given for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding /sup 18/F-compound by the reaction of acetyl hypofluorite or the corresponding /sup 18/F-compound with 3,4,6-tri-0-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.

• DOE Contract Number: AC02-76CH00016
• Assignee: EDB-84-030565
• Application Number: ON: DE84006187
• OSTI ID: 5446138
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
GLUCOSE
LABELLING
FLUORINE 18
ORGANIC FLUORINE COMPOUNDS
ALDEHYDES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
CARBOHYDRATES
FLUORINE ISOTOPES
HEXOSES
HOURS LIVING RADIOISOTOPES
ISOTOPES
LIGHT NUCLEI
MONOSACCHARIDES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
RADIOISOTOPES
SACCHARIDES
400702* - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials