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Variation in baseline sister chromatid exchange frequencies in humans

Conference ·
OSTI ID:5438633
The lymphocyte is a surrogate cell that is routinely used to measure sister chromatid exchange (SCE) frequencies in humans. Our interests have focused on identifying sources of variability in human lymphocyte SCE frequencies, quantifying the magnitude of the variation, and understanding how it might affect the interpretation of data from mutagen-exposed groups. We have measured lymphocyte SCE frequencies in more than 900 blood samples from over 500 individuals. 5 refs., 3 figs., 2 tabs.
Research Organization:
Lawrence Livermore National Lab., CA (USA)
DOE Contract Number:
W-7405-ENG-48
OSTI ID:
5438633
Report Number(s):
UCRL-92836; CONF-8506137-9; ON: DE85016084
Country of Publication:
United States
Language:
English