Radiation therapy treatment of Stage I and II extranodal non-Hodgkin's lymphoma of the head and neck. [Efficacy and complications]

Journal Article · Fri Feb 15 04:00:00 EST 1980 · Cancer; (United States)

OSTI ID:5408426

Mill, W B; Lee, F A; Franssila, K O

We have reviewed the records of 76 patients with Stage I or II extranodal non-Hodgkin's lymphoma who were referred to the Division of Radiation Oncology, Mallinckrodt Institute of Radiology, during the years 1964 through 1974. The histologic slides were reviewed in the 67 cases in which they were available. Forty-three percent of Ann Arbor Stage I and II patients relapsed after primary radiation treatment. Seventy-three percent of these failed in sites distant from the irradiated volume. Failures in the treated volume were infrequent (7%) except in those patients presenting with primary lesions of the brain (4/5). Those patients presenting with lesions of Waldeyer's ring experienced a decrease in survival with increasing tumor size. Because of the high rate of failure in distant sites with tumors in the lingual and palatine tonsils, we are recommending the study of adjuvant chemotherapy in these cases, after primary radiation treatment.

• Research Organization: Washington Univ. School of Medicine, St. Louis, MO
• OSTI ID: 5408426
• Journal Information: Cancer; (United States), Journal Name: Cancer; (United States) Vol. 45:4; ISSN CANCA
• Country of Publication: United States
• Language: English

Related Subjects

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560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARIES
CATARACTS
CENTRAL NERVOUS SYSTEM
COBALT 60
COBALT ISOTOPES
CORNEA
CRYSTALLINE LENS
DATA
DATA COMPILATION
DATA FORMS
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
ELECTRONS
ELEMENTARY PARTICLES
EXTERNAL IRRADIATION
EYES
FERMIONS
FRACTIONATED IRRADIATION
GAMMA RADIATION
GLANDS
HEAD
INFLAMMATION
INFORMATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOLATED VALUES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEPTONS
LOCAL IRRADIATION
LYMPHOMAS
MEDICINE
MINUTES LIVING RADIOISOTOPES
MUCOUS MEMBRANES
MYELITIS
NECK
NEOPLASMS
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NUCLEAR MEDICINE
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORAL CAVITY
ORGANS
PARTIAL BODY IRRADIATION
PATHOLOGICAL CHANGES
PATIENTS
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SALIVARY GLANDS
SENSE ORGANS
SENSE ORGANS DISEASES
SIDE EFFECTS
SPINAL CORD
TEETH
THERAPY
YEARS LIVING RADIOISOTOPES