Stages I and II non-Hodgkin's lymphomas of Waldeyer's ring and the neck

Journal Article · Sat Dec 01 04:00:00 EST 1984 · Am. J. Clin. Oncol.; (United States)

DOI:https://doi.org/10.1097/00000421-198412000-00009· OSTI ID:5750469

Kong, J S; Fuller, L M; Butler, J J; Barton, J H; Robbins, K T; Velasquez, W M; Sullivan, J A

In a previous communication results were reported for patients with localized extranodal presentations of non-Hodgkin's lymphomas of the head and neck who were admitted between 1961-1969. This review describes the larger experience from 1947-1982 in treating 137 Stages I and II Waldeyer's ring patients whose slides were available for reclassification according to the modified Rappaport System. All of these patients were treated definitively as follows: radiotherapy only, 113 patients; radiotherapy and combination chemotherapy, 17 patients; chemotherapy only, seven patients. The overall 5-year survival was 50%. Significant differences were determined for specific subgroups. For patients staged after lymphangiography, the 5-year survival was 67% as compared with 32% for non-lymphangiogram staged patients. Stage (Ann Arbor) also influenced results. The 5-year survival figure for Stage I was 70% as compared with 42% for Stage II. The combination of extent of disease in Waldeyer's ring and the status of the neck had a major impact on survival. When the disease was staged according to the TNMAJCC System, the 5-year survivals were: 75% for T1-T2-TX N0; 53% for T1-T2-TX N+; 54% for T3-T4 N0; and 36% for T3-T4 N+. Also, results for tonsil (52%) and base of tongue (66%) disease were better than for disease involving the nasopharynx (39%) or multiple sites (25%). Treatment also influenced survivals and disease-free survivals. The best results were obtained in patients who were treated with radiotherapy and combination chemotherapy. The 5-year survival and disease-free survival figures were 78% and 69%, respectively.

• Research Organization: Univ. of Texas M.D. Anderson Hospital, Houston
• OSTI ID: 5750469
• Journal Information: Am. J. Clin. Oncol.; (United States), Journal Name: Am. J. Clin. Oncol.; (United States) Vol. 7:6; ISSN AJCOD
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BODY AREAS
CHEMOTHERAPY
CLASSIFICATION
DIAGNOSIS
DISEASES
DOCUMENT TYPES
EVALUATION
HEAD
MEDICINE
NECK
NEOPLASMS
NUCLEAR MEDICINE
PATIENTS
RADIOLOGY
RADIOTHERAPY
REVIEWS
SURVIVAL CURVES
THERAPY