Case-control study of bladder cancer in Massachusetts among populations receiving chlorinated and chloraminated drinking water

Technical Report · Sun Jan 01 04:00:00 EST 1989

OSTI ID:5404321

Zierler, S; Feingold, L; Danley, R A; Craun, G

Studies of the occurrence of bladder cancer in relation to exposure to chlorinated drinking water, in general, have found a small excess frequency of bladder cancer among consumers of chlorinated drinking water. Despite near consistent findings of a small positive association, interpretation of the association has been cautious because of the inability to control for potential confounding by unmeasured differences in surface and ground water, as the index frequently used for exposure to levels of chlorination in drinking water compares chlorinated surface water to unchlorinated ground water. The authors undertook a case-control study to collect detailed data on residential history that was obtained from telephone interviews with informants of 614 individuals who died of primary bladder cancer and 1,074 individuals who died of other causes. The study was based in an area where surface water has been disinfected with either chlorine or a combination of chlorine and ammonia (chloramine) since 1938.

• Research Organization: Brown Univ., Providence, RI (USA). Dept. of Community Health
• OSTI ID: 5404321
• Report Number(s): PB-89-221204/XAB
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMMONIA
BIOLOGICAL EFFECTS
BLADDER
BODY
CARCINOGENS
CHEMICAL REACTIONS
CHLORINATION
CHLORINE
DEMOGRAPHY
DISEASES
DRINKING WATER
ELEMENTS
EPIDEMIOLOGY
FEDERAL REGION I
GROUND WATER
HALOGENATION
HALOGENS
HYDRIDES
HYDROGEN COMPOUNDS
MASSACHUSETTS
MORTALITY
NEOPLASMS
NITROGEN COMPOUNDS
NITROGEN HYDRIDES
NONMETALS
NORTH AMERICA
ORGANS
OXYGEN COMPOUNDS
SAMPLING
SURFACE WATERS
SURVEYS
TOXICITY
URINARY TRACT
USA
WATER
WATER TREATMENT