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G2-delay after irradiation with alpha-particles as studied in synchronized cultures and by the bromodeoxyuridine-33258H technique

Journal Article · · Cytometry (Baltimore); (United States)
OSTI ID:5389342
Division delay of mouse L-929 fibroblasts after alpha-irradiation is due to a pronounced lengthening of their G2-phase. Experiments on synchronously and asynchronously growing cultures revealed a cell cycle phase-dependent sensitivity of this effect: Cells irradiated in G2 or at the G1/S border suffered a longer G2-delay than cells irradiated at mid- or late-S. Progression through G2 was nearly normal at doses up to 0.3 Gy if cells were exposed during G1 phase.
Research Organization:
Nuclear Research Center Karlsruhe, Institute for Genetics and Toxicology, FRG
OSTI ID:
5389342
Journal Information:
Cytometry (Baltimore); (United States), Journal Name: Cytometry (Baltimore); (United States) Vol. 2:3; ISSN CYTOD
Country of Publication:
United States
Language:
English