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Role of direct and mediated effects of ionizing radiation in the mechanism of formation of macropolycytes. [X rays; rats]

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5388463
; ; ;
A cytofluorimetric study was made of DNA content of nuclei of mature neutrophil granulocytes in the bone marrow of rats exposed to 1000 and 2000 rad radiation with the hind limbs shielded. It was shown that production of leukocytes with high DNA content (4 and 8 s) in bone marrow is related to the direct and mediated (abscopal) effect of radiation. The obtained data warrant also the belief that formation of polyploid forms of granulocytes is due to injury to the cell cycle mainly in the G/sub 2/ period.
Research Organization:
Tomsk State Medical Inst., USSR
OSTI ID:
5388463
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:4; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSCOPAL RADIATION EFFECTS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY
BODY AREAS
BODY FLUIDS
BONE MARROW
CELL CYCLE
DATA
DATA FORMS
DNA
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
INFORMATION
INJURIES
IONIZING RADIATIONS
IRRADIATION
ISOLATED VALUES
LEGS
LETHAL IRRADIATION
LEUKOCYTES
LIMBS
MAMMALS
MATERIALS
NEUTROPHILS
NUCLEIC ACIDS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANS
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RATS
RODENTS
SHIELDING
TISSUES
VERTEBRATES
WHOLE-BODY IRRADIATION
X RADIATION