Comparison of rest and exercise radionuclide angiocardiography and exercise treadmill testing for diagnosis of anatomically extensive coronary artery disease

Journal Article · Wed Jun 01 04:00:00 EDT 1983 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.67.6.1204· OSTI ID:5351960

Campos, C T; Chu, H W; D'Agostino, Jr, H J; Jones, R H

The accuracy of rest and exercise radionuclide angiocardiography (RNA) and exercise treadmill testing (ETT) for diagnosis of three-vessel or left main coronary artery disease (extensive CAD) was determined in 544 patients. ETT and RNA sensitivities were similar (88% vs 92%, NS), but ETT was more specific than RNA (46% vs 34%, p less than 0.01). The prevalence of extensive CAD in patients with a positive treadmill (41%) increased only 3% when the RNA was also positive. However, in the 292 patients with a negative or indeterminate ETT, a positive RNA increased this prevalence from 16% to 23%, while a negative RNA decreased this prevalence to 5%. These results support the initial use of ETT followed by RNA if the treadmill is negative or indeterminate for diagnosis in a population with a high prevalence of extensive CAD. This approach separates patients into subgroups with a high or low probability of extensive CAD.

• Research Organization: Department of Surgery, Duke University Medical Center, Durham, North Carolina
• OSTI ID: 5351960
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 67:6; ISSN CIRCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BIOLOGICAL STRESS
BLOOD VESSELS
BODY
CARDIOGRAPHY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
CORONARIES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
EXERCISE
ISOTOPES
ORGANS
RADIOCARDIOGRAPHY
TECHNETIUM ISOTOPES
USES