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Solid phase double-antibody radioimmunoassay procedure

Patent ·
OSTI ID:5335026
The present invention is concerned with the radioimmunoassay (RIA) procedure for assaying body fluid content of an antigenic substance which may either be an antigen itself or a hapten capable of being converted, such as by means of reaction with a protein, to an antigenic material. The present invention is concerned with a novel and improved modification of a double-antibody RIA technique in which there is a first antibody that is specific to the antigenic substance suspected to be present in a body fluid from which the assay is intended. The second antibody, however, is not specific to the antigenic substance or analyte, but is an antibody against the first antibody.
Assignee:
Rohm and Hass Co.
Patent Number(s):
US 4048298
OSTI ID:
5335026
Country of Publication:
United States
Language:
English

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