Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Cytogenetic measurements of the relative biological effectiveness of tritium. Research report No. INFO-0287

Technical Report ·
OSTI ID:5318203
;
Workers in a nuclear reactor facility are exposed to a variety of radiations, including beta radiation from tritiated water. This is important in Canada because deuterium oxide in a CANDU reactor generates tritium. This study was designed to evaluate the biological effectiveness of tritium vs. X-rays to provide information for a cytogenetic estimate of radiation doses received by atomic energy workers and for estimates of genetic hazard to these workers. Measurements were made using CBA/H mice of cytogenetic damage in somatic cells as seen by the induction of chromosomal aberrations in first division metaphases in peripheral blood lymphocytes (the same cells used for biological dosimetry in atomic radiation workers or radiation accidents); and of heritable genetic damage in germ cells as seen by the induction of translocations in primary spermatocytes.
Research Organization:
Atomic Energy Control Board, Ottawa, ON (Canada)
OSTI ID:
5318203
Report Number(s):
MIC-91-03301/XAB
Country of Publication:
United States
Language:
English

Similar Records

Radiation induced chromosome aberrations in somatic and germ cells of the male marmoset
Conference · Fri Dec 31 23:00:00 EST 1976 · OSTI ID:7103895
Application of mammalian cytogenetics to mutagenicity studies. [Triethylone melamine, x radiation, gamma radiation, LET]
Conference · Fri Dec 31 23:00:00 EST 1976 · OSTI ID:7211824
Cytogenetic analysis of mouse metaphase II oocytes following exposure to tritiated water
Journal Article · Tue Sep 01 00:00:00 EDT 1987 · Radiat. Res.; (United States) · OSTI ID:5845683

Related Subjects

560152 -- Radiation Effects on Animals-- Animals
560162* -- Radionuclide Effects
Kinetics
& Toxicology-- Animals
Plants
Microorganisms
& Cells
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACCIDENTS
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY FLUIDS
CANADA
CANDU TYPE REACTORS
CHROMOSOMAL ABERRATIONS
COMPARATIVE EVALUATIONS
CONNECTIVE TISSUE CELLS
DEVELOPED COUNTRIES
DOSES
ELECTROMAGNETIC RADIATION
EVALUATION
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
GERM CELLS
HAZARDS
HEALTH HAZARDS
HEAVY WATER MODERATED REACTORS
HYDROGEN COMPOUNDS
IONIZING RADIATIONS
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MATERIALS
MICE
MUTATIONS
NORTH AMERICA
OXYGEN COMPOUNDS
PRESSURE TUBE REACTORS
RADIATION ACCIDENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION HAZARDS
RADIATIONS
RADIOINDUCTION
RBE
REACTORS
RODENTS
SOMATIC CELLS
THERMAL REACTORS
TRITIUM COMPOUNDS
VERTEBRATES
WATER
X RADIATION