Carcinoma of the endometrium
Journal Article
·
· Cancer (Philadelphia); (United States)
DOI:https://doi.org/10.1002/1097-0142(19810715)48:1+<575::AID-CNCR2820481322>3.0.CO;2-7·
OSTI ID:5308367
Controversy continues as to how and when radiation therapy can best be combined with surgery in order to improve treatment results in patients, with endometrial cancer. Various prognostic factors--tumor grade, depth of myometrial invasion, size of the uterine cavity, and the presence of nodal or parametrial spread--must all be considered when planning therapy. Well-differentiated Stage IA endometrial cancers hav an excellent prognosis when treated by surgery alone. Evidence suggests, however, that all other Stage I tumors benefit from combined radiation and surgical treatment. Patients with advanced stages of disease are candidates for combined surgery and radiation or radiation alone, owing to the high frequency of pelvic node involvement. Areas of active investigation include the addition of systemic therapy in patients with Stage III disease and the evaluation of extended field radiation in patients with histologically confirmed high pelvic or paraaortic nodal involvement.
- OSTI ID:
- 5308367
- Journal Information:
- Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 48:2; ISSN CANCA
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
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NUCLEAR MEDICINE
ORGANS
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PATHOLOGY
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550900 -- Pathology
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BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARCINOMAS
DISEASES
EXTERNAL IRRADIATION
FEMALE GENITALS
IRRADIATION
LYMPH NODES
LYMPHATIC SYSTEM
MEDICINE
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NUCLEAR MEDICINE
ORGANS
PARTIAL BODY IRRADIATION
PATHOLOGY
PATIENTS
PLANNING
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY
UTERUS