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Estimates of left-ventricular volumes by equilibrium radionuclide angiography: importance of attenuation correction

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:5299445
; ; ; ; ;
To compare the accuracy of attenuated and attenuation-corrected equilibrium radionuclide angiographic (RNA) left ventricular (LV) volume estimates, the authors studied 23 consecutive patients with biplane contrast cineangiography (CINE). Attenuated RNA end-diastolic (ED) and end-systolic (ES) volumes were calculated from background-corrected ED and ES counts obtained from hand-drawn regions of interest that were normalized to cardiac cycles processed, frame rate, and blood activity. A simple, geometric attenuation correction was performed to obtain attenuation-corrected RNA LV volumes. The attenuated and attenuation-corrected RNA LV EDV estimates correlated with the CINE LV EDVs; however, the attenuation-corrected RNA LV EDV estimates also correlated with the CINE LV ESVs, but the attenuation-corrected RNA LV ESV estimates more closely. Also, the average attenuation-corrected RNA LV EDV did not differ significantly from the mean CINE LV EDV. Attenuated and attenuation-corrected RNA LV ESV estimates correlated more closely. Also, the average attenuation-corrected RNA LV ESV did not differ significantly from the mean biplane CINE LV ESV.
Research Organization:
Univ. of Texas Health Science Center, San Antonio
OSTI ID:
5299445
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:1; ISSN JNMEA
Country of Publication:
United States
Language:
English

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