Novel polycatecholamide chelating agents

Patent · Mon Aug 24 00:00:00 EDT 1981

OSTI ID:5294674

Weitl, F L; Raymond, K N

Novel polybenzamide compounds useful for in vitro or in vivo chelation are described. Formulas of the compounds are given. To prepare them polyamines are reacted with 2,3-dimethoxy benzoyl chloride unsubstituted or substituted with SO/sub 3/H, SO/sub 3/M, NO/sub 2/, CO/sub 2/H or CO/sub 2/M as desired is reacted with a polyamine in an inert solvent then demethylated with BBr/sub 3/ or BCl/sub 3/ in an inert solvent. Where compounds symmetrically substituted on the terminal N's are desired, the polyamine is first reductively alkylated by reaction with an aldehyde or ketone and the resulting Schiff base is hydrogenated.

• DOE Contract Number: W-7405-ENG-48
• Assignee: Dept. of Energy
• Application Number: ON: DE82013613
• OSTI ID: 5294674
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ACTINIDES
REMOVAL
AMIDES
CHEMICAL PREPARATION
CHELATING AGENTS
AMINES
IN VITRO
IN VIVO
POLYMERS
PYROCATECHOL
SEPARATION PROCESSES
AROMATICS
DEVELOPERS
ELEMENTS
HYDROXY COMPOUNDS
METALS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHENOLS
POLYPHENOLS
SYNTHESIS
560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)
054000 - Nuclear Fuels- Health & Safety
400301 - Organic Chemistry- Chemical & Physicochemical Properties- (-1987)