Cf-252 neutron brachytherapy of short duration for bulky neck tumors
Journal Article
·
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
Cf-252 (Cf) neutron brachytherapy (NT) was tested for treatment of bulky neck tumor masses in 13 patients. Complete regression (CR) or partial regression (PR) was obtained in 100% and local control in 85%. Tumors cleared rapidly and completely after an implant therapy of 4-7 hrs. Short duration Cf-NT can produce rapid and complete clearance of bulky tumors. Efficacy was independent of the implant time duration and without unusual adverse side effects or complications. The median survival time (MST) of patients dying of their disease was 6.8 months and 48% of treated patients survived greater than 18 months despite their advanced diseased status.
- Research Organization:
- Univ. of Kentucky Medical Center, Lexington
- OSTI ID:
- 5268756
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 5; ISSN IOBPD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
BODY
BODY AREAS
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
DISEASES
EFFICIENCY
EVEN-EVEN NUCLEI
HEAVY NUCLEI
IMPLANTS
ISOTOPES
MEDICINE
NECK
NEOPLASMS
NEUTRON THERAPY
NUCLEAR MEDICINE
NUCLEI
PATIENTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
YEARS LIVING RADIOISOTOPES
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
BODY
BODY AREAS
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
DISEASES
EFFICIENCY
EVEN-EVEN NUCLEI
HEAVY NUCLEI
IMPLANTS
ISOTOPES
MEDICINE
NECK
NEOPLASMS
NEUTRON THERAPY
NUCLEAR MEDICINE
NUCLEI
PATIENTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
YEARS LIVING RADIOISOTOPES