Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Malignant melanoma of the eye: treatment of posterior uveal lesions by Co-60 plaque radiotherapy versus enucleation

Conference · · Radiology; (United States)
OSTI ID:5265196
; ; ; ; ; ; ;

Survival rates and visual acuity of 100 patients treated for posterior uveal malignant melanoma by cobalt-60 plaque radiotherapy were compared with 150 patients treated by enucleation for the same disease. Life-table comparisons of the entire group showed significant differences in survival rates, with plaque radiotherapy patients appearing to fare better. However, when patients with small or medium tumors were compared, only slight differences were seen, implying that criteria used to select patients for treatment may affect interpretation. The two groups were also compared using the Cox proportional hazards model, which predicts survival based on the impact of clinical variables. In this analysis, the survival rates of the plaque radiotherapy group were no worse than those of the enucleation group. The advantage of conservative therapy lies in the potential to preserve useful vision over a considerable time.

Research Organization:
Hahnemann Univ. College of Medicine, Philadelphia, PA
OSTI ID:
5265196
Report Number(s):
CONF-851152-
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 156:3; ISSN RADLA
Country of Publication:
United States
Language:
English

Similar Records

Cobalt-60 plaque radiotherapy vs enucleation for posterior uveal melanoma
Journal Article · Tue May 15 00:00:00 EDT 1990 · American Journal of Ophthalmology; (USA) · OSTI ID:7044055
Enucleation vs cobalt plaque radiotherapy for malignant melanomas of the choroid and ciliary body
Journal Article · Thu May 01 00:00:00 EDT 1986 · Arch. Ophthalmol. (Chicago); (United States) · OSTI ID:5618789
Uveal Melanoma Recurrence After Fractionated Proton Beam Therapy: Comparison of Survival in Patients Treated With Reirradiation or With Enucleation
Journal Article · Mon Feb 28 23:00:00 EST 2011 · International Journal of Radiation Oncology, Biology and Physics · OSTI ID:21491618

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
COBALT 60
COBALT ISOTOPES
COMPARATIVE EVALUATIONS
DISEASES
ELECTROMAGNETIC RADIATION
EYES
FACE
GAMMA RADIATION
HEAD
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MELANOMAS
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SENSE ORGANS
SURGERY
SURVIVAL TIME
THERAPY
UVEA
VISION
YEARS LIVING RADIOISOTOPES