Adverse health effects in workers exposed to cadmium

Journal Article · Wed Jan 01 04:00:00 EST 1992 · American Journal of Industrial Medicine; (United States)

DOI:https://doi.org/10.1002/ajim.4700210408· OSTI ID:5263813

Kahan, E; Derazne, E; Rosenboim, J; Ashkenazi, R; Ribak, J ^[1]

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1. Institute for Occupational Health, Tel Aviv University, (Israel)

One hundred fifty-two workers who had been exposed to different levels of cadmium (Cd) absorption (blood Cd mean 16.34 micrograms/L, median 11.0 micrograms/L) in a factory making nickel-cadmium batteries were studied. A physical evaluation, as well as blood and urine cadmium and N-acetyl-beta-D-glucosaminidase (NAG), and other routine laboratory tests were performed in order to assess the relationship between different levels of exposure to occupational cadmium and potential cadmium-induced renal damage and other adverse health effects. We found significant correlation between levels of cadmium exposure and a selected group of symptoms and signs. The best predictor of this group of symptoms and signs was an indicator called internal dose index (Cd x exposure time). This indicator appears as the strongest, even after control by confounding factors, such as age and smoking. It is concluded that this index can be used for biological monitoring.

• OSTI ID: 5263813
• Journal Information: American Journal of Industrial Medicine; (United States), Journal Name: American Journal of Industrial Medicine; (United States) Vol. 21:4; ISSN 0271-3586; ISSN AJIMD
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
HAZARDS
HEALTH HAZARDS
METABOLISM
METALLURGY
METALS
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
PERSONNEL
SYMPTOMS