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U.S. Department of Energy
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Accessory cell requirements for the generation of cytolytic T lymphocytes

Journal Article · · J. Immunol.; (United States)
OSTI ID:5263650
A system is presented that may simplify the study of accessory cell requirements for CTL generation. Cortisone resistant (CR) thymocytes containing alloreactive CTL precursors do not respond to allogeneic tumor cells unless non-T accessory cells are added to culture. In addition, splenic T cells do not respond to allogeneic tumor cells in the absence of non-T accessory cells. These accessory cells share several properties of macrophages.
Research Organization:
Univ of Chicago, IL
OSTI ID:
5263650
Journal Information:
J. Immunol.; (United States), Journal Name: J. Immunol.; (United States) Vol. 122:6; ISSN JOIMA
Country of Publication:
United States
Language:
English