Chronic manganese intoxication

Journal Article · Sun Oct 01 04:00:00 EDT 1989 · Archives of Neurology; (USA)

DOI:https://doi.org/10.1001/archneur.1989.00520460090018· OSTI ID:5257147

Huang, C C; Chu, N S; Lu, C S; Wang, J D; Tsai, J L; Tzeng, J L; Wolters, E C; Calne, D B ^[1]

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1. Chang Gung Medical College Hospital, Taipei, Taiwan (China)

We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.

• OSTI ID: 5257147
• Journal Information: Archives of Neurology; (USA), Journal Name: Archives of Neurology; (USA) Vol. 46:10; ISSN 0003-9942; ISSN ARNEA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ASIA
BIOLOGICAL ACCUMULATION
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
CHRONIC EXPOSURE
DISEASES
ELEMENTS
EPIDEMIOLOGY
HAIR
ISLANDS
MANGANESE
MATERIALS
METABOLISM
METALLURGY
METALS
NERVOUS SYSTEM DISEASES
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
ORGANS
PERSONNEL
SKIN
TAIWAN
TOXICITY
TRANSITION ELEMENTS