Accumulation, elimination, and metabolism of dichlorobenzidine in the bluegill sunfish

Journal Article · Mon Dec 31 23:00:00 EST 1979 · Environ. Sci. Technol.; (United States)

DOI:https://doi.org/10.1021/es60161a005· OSTI ID:5243122

Appleton, H T; Sikka, H C

The bioconcentration, elimination, and metabolism of 3,3'-dichlorobenzidine (DCB, a suspected human carcinogen) in bluegill sunfish were studied. Radioactively labeled DCB at 5 ppb in water was rapidly accumulated in the fish. Bioconcentration factors of 495-507 occurred in whole fish after equilibrium (96-168 hr). DCB residues were present in both edible and nonedible portions. DCB or DCB metabolites were not completely eliminated after transfer of fish to clean water. Concentration of DCB in fish may be a human health hazard if fish are eaten. (22 references, 6 tables)

• Research Organization: Syracuse Research Corp, NY
• OSTI ID: 5243122
• Journal Information: Environ. Sci. Technol.; (United States), Journal Name: Environ. Sci. Technol.; (United States) Vol. 14:1; ISSN ESTHA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
AROMATICS
BIOLOGICAL ACCUMULATION
CHLORINATED AROMATIC HYDROCARBONS
FISHES
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
HEALTH HAZARDS
LABELLED COMPOUNDS
METABOLISM
METABOLITES
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
TOXICITY
TRACE AMOUNTS
VERTEBRATES