Bioaccumulation of cinmethylin in bluegill sunfish

Journal Article · Mon Jan 01 04:00:00 EST 1990 · Journal of Agricultural and Food Chemistry; (USA)

DOI:https://doi.org/10.1021/jf00091a071· OSTI ID:6524648

Lee, P W ^[1]; Forbis, A D; Franklin, L ^[2]

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1. E.I. du Pont de Nemours and Co., Inc., Wilmington, DE (USA)
2. Analytical Bio-Chemistry Labs., Inc., Columbia, MD (USA)

Technical cinmethylin and Cinch 7EC herbicide showed low toxicity against various aquatic organisms. The bioaccumulation potential of ({sup 14}C)cinmethylin in the bluegill sunfish under a dynamic flow-through system at a constant concentration of 0.1 mg/L was examined. A rapid uptake of radioactivity was observed. Tissue residues plateaued after 3 days, and the mean tissue residues after 28 days of exposure were 35, 12, and 58 {mu}g/g (ppm) for the whole fish, fillet, and viscera, respectively. The corresponding bioconcentration factors for the above tissues were 360, 120, and 600, respectively. Greater than 99% of the tissue residues was eliminated from the exposed fish after the 14-day depuration period. In addition to ({sup 14}C)cinmethylin, major metabolites isolated from the treated fish were {alpha}-carboxycinmethylin and 8-hydroxy-{alpha}-carboxycinmethylin. o-Toluic acid and {alpha}-hydroxycinmethylin were observed as minor components.

• OSTI ID: 6524648
• Journal Information: Journal of Agricultural and Food Chemistry; (USA), Journal Name: Journal of Agricultural and Food Chemistry; (USA) Vol. 38:1; ISSN JAFCA; ISSN 0021-8561
• Country of Publication: United States
• Language: English

Related Subjects

553003* -- Agriculture & Food Technology-- Pest & Disease Control-- (1987-)
60 APPLIED LIFE SCIENCES
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL ACCUMULATION
CARBON 14 COMPOUNDS
FISHES
HERBICIDES
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
METABOLISM
METABOLITES
PESTICIDES
TOXICITY
TRACER TECHNIQUES
UPTAKE
VERTEBRATES