Cyclotrons and radiopharmaceuticals in positron emission tomography. Council on Scientific Affairs. Report of the Positron Emission Tomography Panel

Journal Article · Thu Mar 24 23:00:00 EST 1988 · JAMA, J. Am. Med. Assoc.; (United States)

OSTI ID:5237912

Positron emission tomography (PET) can probe biochemical pathways in vivo and can provide quantitative data; for that purpose, tracers labeled with positron-emitting radioisotopes are essential. This report describes the tracers that are being used or that may have future use, their production by cyclotrons, and other needed resources for PET imaging. Current routine and automated methods for convenient production of labeled compounds, coupled with simple computer-controlled accelerators, can support the creation of clinical PET centers in any large medical institution, obviating the need for in-depth research teams. An alternate approach involves the development of regional centers that provide in-house service and that supply fluorine 18- and carbon 11-labeled compounds to nearby hospitals with PET machines.63 references.

• OSTI ID: 5237912
• Journal Information: JAMA, J. Am. Med. Assoc.; (United States), Journal Name: JAMA, J. Am. Med. Assoc.; (United States) Vol. 259:12; ISSN JAMAA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCELERATORS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
BRAIN
CARBON 11
CARBON ISOTOPES
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CHEMICAL PREPARATION
COMPUTERIZED TOMOGRAPHY
CYCLIC ACCELERATORS
CYCLOTRONS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
FLUORINE 18
FLUORINE ISOTOPES
HEART
HOURS LIVING RADIOISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NERVOUS SYSTEM
NUCLEI
ODD-ODD NUCLEI
ORGANS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
RADIOPHARMACEUTICALS
SYNTHESIS
TOMOGRAPHY