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Influence of DNA repair and replication inhibitors on incorporation of 2-/sup 14/C-thymidine in pea root DNA following exposure to gamma radiation

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5237335
;
A study was made of distinctions of DNA synthesis in ..gamma..-irradiated pea roots in the post-radiation period. It was found that there is additional DNA synthesis in the roots 24 h after irradiation. Use of inhibitors of replicative (hydroxyurea and mitomycin C) and repair (caffeine, acriflavine) synthesis of DNA, as well as postradiation incubation without saccharose in the nutrient medium, revealed that the observed additional DNA synthesis is due to both repair and replicative synthesis of DNA.
Research Organization:
Inst. of Plant Physiology, Kiev
OSTI ID:
5237335
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:2; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

560111* -- Radiation Effects on Biochemicals-- In Vitro-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACRIDINES
ACRIFLAVINE
AMIDES
AMINES
ANTIBIOTICS
ANTIMITOTIC DRUGS
AZINES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BIOSYNTHESIS
CAFFEINE
CARBON 14
CARBON ISOTOPES
DNA
DNA REPLICATION
DRUGS
ELECTROMAGNETIC RADIATION
EVEN-EVEN NUCLEI
FLAVINES
FOOD
GAMMA RADIATION
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
HYDROXYUREA
IONIZING RADIATIONS
ISOTOPES
LIGHT NUCLEI
MITOMYCIN
NUCLEI
NUCLEIC ACID REPLICATION
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PEAS
PURINES
PYRIDINES
PYRIMIDINES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RECOVERY
REPAIR
RIBOSIDES
ROOTS
SYNTHESIS
THYMIDINE
VEGETABLES
XANTHINES
YEARS LIVING RADIOISOTOPES