Bioavailability of zinc, copper, and manganese from infant diets
A series of trace element absorption experiments were performed using the Sprague-Dawley suckling rat put and infant rhesis monkey (Macaca mulatta) with extrinsic radiolabeling to assess the bioavailability of Zn, Cu, and Mn from infant diets and to examine specific factors that affect absorption of these essential nutrients. Bioavailability of Cu as assessed by 6 h liver uptake (% of /sup 64/Cu dose) was highest from human milk and cow milk based formula and significantly lower from cow milk and soy based formula. Copper bioavailability from infant cereal products as assessed by whole body uptake (% of /sup 64/Cu dose) in d 20 rats, 9 h postintubation, was low compared to the bioavailability from cow milk or human milk alone. /sup 65/Zn uptake in d 20 rats, 9 h postintubation, was significantly lower from cereals fed alone or in combination with cow or human milk as compared to the uptake from the milks fed alone. Zn bioavailability varied among cereal diets, (lowest from cereals containing phytate and highest from cereal/fruit products). Mn bioavailability from infant diets was assessed using a modified suckling rat pup model. Bioavailability (24 h whole body retention of /sup 54/Mn) was high from all milks and commercial formulas tested.
- Research Organization:
- California Univ., Davis (USA)
- OSTI ID:
- 5230651
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
AGE GROUPS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL AVAILABILITY
BIOLOGICAL MATERIALS
BIOLOGICAL MODELS
BODY FLUIDS
CHILDREN
COPPER
COPPER 64
COPPER ISOTOPES
DAYS LIVING RADIOISOTOPES
DIET
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
FOOD
HOURS LIVING RADIOISOTOPES
INFANTS
INTERMEDIATE MASS NUCLEI
INTESTINAL ABSORPTION
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MANGANESE
MANGANESE 54
MANGANESE ISOTOPES
MATERIALS
METALS
MILK
MONKEYS
NUCLEI
NUTRIENTS
ODD-ODD NUCLEI
PRIMATES
RADIOISOTOPES
RATS
RODENTS
TRACE AMOUNTS
TRACER TECHNIQUES
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES
ZINC