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Title: Bioavailability of zinc, copper, and manganese from infant diets

Abstract

A series of trace element absorption experiments were performed using the Sprague-Dawley suckling rat put and infant rhesis monkey (Macaca mulatta) with extrinsic radiolabeling to assess the bioavailability of Zn, Cu, and Mn from infant diets and to examine specific factors that affect absorption of these essential nutrients. Bioavailability of Cu as assessed by 6 h liver uptake (% of /sup 64/Cu dose) was highest from human milk and cow milk based formula and significantly lower from cow milk and soy based formula. Copper bioavailability from infant cereal products as assessed by whole body uptake (% of /sup 64/Cu dose) in d 20 rats, 9 h postintubation, was low compared to the bioavailability from cow milk or human milk alone. /sup 65/Zn uptake in d 20 rats, 9 h postintubation, was significantly lower from cereals fed alone or in combination with cow or human milk as compared to the uptake from the milks fed alone. Zn bioavailability varied among cereal diets, (lowest from cereals containing phytate and highest from cereal/fruit products). Mn bioavailability from infant diets was assessed using a modified suckling rat pup model. Bioavailability (24 h whole body retention of /sup 54/Mn) was high from all milks andmore » commercial formulas tested.« less

Authors:
Publication Date:
Research Org.:
California Univ., Davis (USA)
OSTI Identifier:
5230651
Resource Type:
Thesis/Dissertation
Resource Relation:
Other Information: Thesis (Ph. D.)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; COPPER; BIOLOGICAL AVAILABILITY; INTESTINAL ABSORPTION; MANGANESE; ZINC; BIOLOGICAL MODELS; COPPER 64; DIET; INFANTS; MANGANESE 54; MILK; MONKEYS; NUTRIENTS; RATS; TRACE AMOUNTS; TRACER TECHNIQUES; ABSORPTION; AGE GROUPS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY FLUIDS; CHILDREN; COPPER ISOTOPES; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; ELEMENTS; FOOD; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MANGANESE ISOTOPES; MATERIALS; METALS; NUCLEI; ODD-ODD NUCLEI; PRIMATES; RADIOISOTOPES; RODENTS; TRANSITION ELEMENTS; UPTAKE; VERTEBRATES; 560300* - Chemicals Metabolism & Toxicology; 550501 - Metabolism- Tracer Techniques

Citation Formats

Bell, J G. Bioavailability of zinc, copper, and manganese from infant diets. United States: N. p., 1987. Web.
Bell, J G. Bioavailability of zinc, copper, and manganese from infant diets. United States.
Bell, J G. Thu . "Bioavailability of zinc, copper, and manganese from infant diets". United States.
@article{osti_5230651,
title = {Bioavailability of zinc, copper, and manganese from infant diets},
author = {Bell, J G},
abstractNote = {A series of trace element absorption experiments were performed using the Sprague-Dawley suckling rat put and infant rhesis monkey (Macaca mulatta) with extrinsic radiolabeling to assess the bioavailability of Zn, Cu, and Mn from infant diets and to examine specific factors that affect absorption of these essential nutrients. Bioavailability of Cu as assessed by 6 h liver uptake (% of /sup 64/Cu dose) was highest from human milk and cow milk based formula and significantly lower from cow milk and soy based formula. Copper bioavailability from infant cereal products as assessed by whole body uptake (% of /sup 64/Cu dose) in d 20 rats, 9 h postintubation, was low compared to the bioavailability from cow milk or human milk alone. /sup 65/Zn uptake in d 20 rats, 9 h postintubation, was significantly lower from cereals fed alone or in combination with cow or human milk as compared to the uptake from the milks fed alone. Zn bioavailability varied among cereal diets, (lowest from cereals containing phytate and highest from cereal/fruit products). Mn bioavailability from infant diets was assessed using a modified suckling rat pup model. Bioavailability (24 h whole body retention of /sup 54/Mn) was high from all milks and commercial formulas tested.},
doi = {},
url = {https://www.osti.gov/biblio/5230651}, journal = {},
number = ,
volume = ,
place = {United States},
year = {1987},
month = {1}
}

Thesis/Dissertation:
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