Effect of infant cereals on zinc and copper absorption during weaning

Journal Article · Thu Oct 01 00:00:00 EDT 1987 · Am. J. Dis. Child.; (United States)

DOI:https://doi.org/10.1001/archpedi.1987.04460100106041· OSTI ID:6017445

Bell, J G; Keen, C L; Loennerdal, B

Zinc and copper absorption from five infant cereal products mixed with water, human milk, or cow's milk was measured using an in vivo absorption model (rat pup) involving gastric intubation of extrinsically radiolabeled diets. Whole-body copper 64 uptake, nine hours after intubation, ranged from 14% to 31% of the dose given for the different cereal combinations. The resultant bioavailability of copper from human milk-cereal combinations (23% to 26%) was significantly lower than that from human milk alone (38%). Whole-body zinc 65 uptake, nine hours after intubation, ranged from 13% to 54% of the dose given for the different cereal combinations. These values were significantly lower than the whole-body zinc 65 uptake from milk alone (61%). Zinc availability was lower (13% to 25%) from dry cereal combinations that contained phytic acid (oatmeal and high-protein varieties) compared with the ready-to-serve cereal-fruit combinations (24% to 54%). The highest zinc uptake (37% to 54%) was from rice-fruit combinations that do not contain phytic acid. We estimated the amounts of zinc and copper that would be absorbed from these cereal products and speculated on the potential impact of these foods on the weaning infant's zinc and copper nutriture. Depending on the feeding practices employed during the weaning period, it is apparent that infant cereals may compromise utilization of zinc and copper from milk diets during weaning.

• Research Organization: Univ. of California, Davis
• OSTI ID: 6017445
• Journal Information: Am. J. Dis. Child.; (United States), Vol. 141:10
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
COPPER
INTESTINAL ABSORPTION
METABOLISM
ZINC
BIOLOGICAL AVAILABILITY
BIOLOGICAL MODELS
CATTLE
CEREALS
COPPER 64
MAN
MILK
NUTRIENTS
PHYTIC ACID
RATS
TRACER TECHNIQUES
ZINC 65
ABSORPTION
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY FLUIDS
COPPER ISOTOPES
DAYS LIVING RADIOISOTOPES
DOMESTIC ANIMALS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
ESTERS
EVEN-ODD NUCLEI
FOOD
GRASS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MATERIALS
METALS
NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
PHOSPHORIC ACID ESTERS
PLANTS
PRIMATES
RADIOISOTOPES
RODENTS
RUMINANTS
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES
ZINC ISOTOPES
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550501 - Metabolism- Tracer Techniques