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Influence of essential elements on manganese intoxication

Journal Article · · Bull. Environ. Contam. Toxicol.; (United States)
DOI:https://doi.org/10.1007/BF01607459· OSTI ID:5213300
; ;
With a view to explore the influence of essential metals in manganese intoxication, the effect of calcium, iron or zinc supplementation on the uptake of manganese and on the activity of manganese sensitive enzymes, succinic dehydrogenase and cytochrome oxidase in brain and liver of rat was investigated. The choice of the two mitochondrial enzymes was based on the fact that the mitochondria are the chief site of manganese accumulation and their activity in brain, liver and blood of rats is significantly influenced by manganese.
Research Organization:
Industrial Toxicology Research Center, Lucknow, India
OSTI ID:
5213300
Journal Information:
Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 32:1; ISSN BECTA
Country of Publication:
United States
Language:
English

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Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH METAL COMPOUNDS
ANIMALS
BIOCHEMISTRY
BIOLOGICAL ACCUMULATION
BIOLOGICAL EFFECTS
BODY
BRAIN
CALCIUM CHLORIDES
CALCIUM COMPOUNDS
CALCIUM HALIDES
CENTRAL NERVOUS SYSTEM
CHEMISTRY
CHLORIDES
CHLORINE COMPOUNDS
DIGESTIVE SYSTEM
ENZYMES
GLANDS
HALIDES
HALOGEN COMPOUNDS
IRON COMPOUNDS
IRON SULFATES
LIVER
MAMMALS
MANGANESE CHLORIDES
MANGANESE COMPOUNDS
MANGANESE HALIDES
NERVOUS SYSTEM
ORGANS
OXIDOREDUCTASES
OXYGEN COMPOUNDS
RATS
RODENTS
SULFATES
SULFUR COMPOUNDS
SYNERGISM
TOXICITY
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
ZINC COMPOUNDS
ZINC SULFATES