Biochemical Effects of Gamma Irradiation on the Succinoxidase System, in vitro
Journal Article
·
· Journal of Radiation Research
The succinoxidase system and each component enzyme, i.e., succinic dehydrogenase and cytochrome oxidase, obtained from the liver of mice and rats and from beef heart, were irradiated in vitro with cobalt-60 gamma rays. Inactivation of the enzyme systems was produced by relatively large doses of gamma irradiation. Succinic dehydrogenase was found to be more radiosensitive than cytochrome oxidase in all preparations. The effect of gamma irradiation on the enzyme systems in mitochondria and nuclei of rat liver was compared. The enzyme systems in the nuclear fraction were relatively more radio sensitive to gamma -ray inactivation than those in the mitochondrial fraction. (auth)
- Research Organization:
- Kyoto Univ.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-024695
- OSTI ID:
- 4023970
- Journal Information:
- Journal of Radiation Research, Journal Name: Journal of Radiation Research Journal Issue: 2 Vol. 1; ISSN 0449-3060
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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