Effect of milk on mercury absorption and gut retention in rats

Journal Article · Wed Oct 31 23:00:00 EST 1979 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01770004· OSTI ID:5209813

Kostial, K ^[1]; Rabar, I; Ciganovic, M; Simonovic, I

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1. Inst. of Medical Research, Pijade, Yugoslavia

The retention of /sup 203/Hg was studied six days after a single oral or intraperitoneal administration to six week old female albino rats fed rat's diet or milk. After oral administration rats on milk diet had a two times higher retention of mercury in the gut-free carcass and a 23 times higher retention in the gut than animals on rat's diet. Changes in diet had very little influence on mercury retention after intraperitoneal administration. The higher gut and carcass retentions of mercury in animals on milk diet could be prevented or reduced by transferring rats from milk diet to rat's diet several days after an oral dose of mercury. These results might be relevant for interpreting high gut and carcass retention after oral administration of some metals in suckling and changes which occur at weaning.

• OSTI ID: 5209813
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 23:4/5; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BODY FLUIDS
DAYS LIVING RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
FOOD
HEAVY NUCLEI
INJECTION
INTAKE
INTRAPERITONEAL INJECTION
ISOTOPES
MAMMALS
MATERIALS
MERCURY
MERCURY 203
MERCURY ISOTOPES
METALS
MILK
NUCLEI
ORAL ADMINISTRATION
RADIOISOTOPES
RATS
RETENTION
RODENTS
VERTEBRATES