Computed tomographic demonstration of the effects of bromocriptine on pituitary microadenoma size

Journal Article · Sat May 01 04:00:00 EDT 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.143.2.7071347· OSTI ID:5176108

Bonneville, J F ^[1]; Poulignot, D; Cattin, F; Couturier, M; Mollet, E; Dietemann, J L

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1. Univ. Hospital of Besancon, France

A group of 17 strictly intrasellar prolactin-secreting pituitary adenomas between 2 and 9 mm in size was examined by computed tomography before and after bromocriptine therapy of 3 months to 1 year duration. These findings were compared with clinical and biological data. Bromocriptine therapy was effective clinically and biologically in 14 of the 17 cases. Of the 15 intrasellar adenomas in nonpregnant patients treated with bromocriptine, six disappeared completely with normalization of the pituitary appearance, five decreased approximately 50% in volume (three showed an increase in density, two a decrease), and four remained unchanged in size (two showed increased density, two showed very low densities).

• OSTI ID: 5176108
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 143:2; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
ANTINEOPLASTIC DRUGS
BIOLOGICAL EFFECTS
BODY
COMPUTERIZED TOMOGRAPHY
CONTRAST MEDIA
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
ENDOCRINE GLANDS
GLANDS
GONADOTROPINS
HORMONES
LTH
NEOPLASMS
ORGANS
PATIENTS
PEPTIDE HORMONES
PITUITARY GLAND
PITUITARY HORMONES
PREGNANCY
SIZE
TOMOGRAPHY