Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates
Patent
·
OSTI ID:516931
The subject invention provides an antibody which specifically binds to the product of a reaction between a labeling substance and a substrate. The subject invention also provides a method of making an immunogen used to produce the antibody of the subject invention. The invention further provides methods of using the subject antibody for detecting an antigen of interest in a sample, for example detecting a protein comprising an amino acid sequence of interest and detecting a nucleic acid molecule comprising a nucleic acid sequence of interest. 8 figs.
- Research Organization:
- University of Vermont
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-88ER60742
- Assignee:
- Columbia Univ., New York, NY (United States)
- Patent Number(s):
- US 5,650,284/A/
- Application Number:
- PAN: 8-403,649
- OSTI ID:
- 516931
- Country of Publication:
- United States
- Language:
- English
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