Morphofunctional study of neurohumoral reactions in the presence of radiation lesion to the heart
Journal Article
·
· Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5166446
The cardiac region of rats was exposed to 600 to 2000 R of local radiation; the rats were killed at intervals up to 10 days later. Observations were made on monoamine oxidase (MAO) activity and content of catecholamines, norepinephine, dopamine, and serotonin in the heart. Observations were also made on the vascular bed and mast cells of the heart and pericardium. Two hrs after irradiation there was an increase in MAO activity and mobilization of amines. Dilatation of capillaries and small veins and constriction of arteries of the heart and pericardium occurred. By the end of the fifth day there was an increase in fluorescence of catecholamines and serotonin in sympathetic nerve endings and mast cells. By the tenth day there was a return to normal of MAO activity and catecholamine content. (HLW)
- Research Organization:
- Central Inst. for Advanced Training of Physicians, Moscow
- OSTI ID:
- 5166446
- Journal Information:
- Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:5; ISSN RADBA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL HORMONES
AMINES
ANIMAL CELLS
ANIMALS
AROMATICS
AZOLES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CATECHOLAMINES
CONNECTIVE TISSUE CELLS
DOPAMINE
DRUGS
ENZYMES
FLUORESCENCE
HEART
HETEROCYCLIC COMPOUNDS
HORMONES
HYDROXY COMPOUNDS
INDOLES
IRRADIATION
LOCAL IRRADIATION
LUMINESCENCE
MAMMALS
MAST CELLS
METABOLISM
MORPHOLOGICAL CHANGES
NERVOUS SYSTEM
NORADRENALINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
OXIDASES
OXIDOREDUCTASES
PHENOLS
POLYPHENOLS
PYRROLES
RADIATION EFFECTS
RADIOPROTECTIVE SUBSTANCES
RATS
RESPONSE MODIFYING FACTORS
RODENTS
SEROTONIN
SOMATIC CELLS
STEROID HORMONES
SYMPATHOMIMETICS
TRYPTAMINES
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL HORMONES
AMINES
ANIMAL CELLS
ANIMALS
AROMATICS
AZOLES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CATECHOLAMINES
CONNECTIVE TISSUE CELLS
DOPAMINE
DRUGS
ENZYMES
FLUORESCENCE
HEART
HETEROCYCLIC COMPOUNDS
HORMONES
HYDROXY COMPOUNDS
INDOLES
IRRADIATION
LOCAL IRRADIATION
LUMINESCENCE
MAMMALS
MAST CELLS
METABOLISM
MORPHOLOGICAL CHANGES
NERVOUS SYSTEM
NORADRENALINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
OXIDASES
OXIDOREDUCTASES
PHENOLS
POLYPHENOLS
PYRROLES
RADIATION EFFECTS
RADIOPROTECTIVE SUBSTANCES
RATS
RESPONSE MODIFYING FACTORS
RODENTS
SEROTONIN
SOMATIC CELLS
STEROID HORMONES
SYMPATHOMIMETICS
TRYPTAMINES
VERTEBRATES