Imaging of the heart using metaiodobenzylguanidine

Journal Article · Sun Jul 01 04:00:00 EDT 1990 · Journal of Thoraric Imaging; (USA)

DOI:https://doi.org/10.1097/00005382-199007000-00007· OSTI ID:6609496

Dae, M W; Botvinick, E H ^[1]

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1. Univ. of California, San Francisco (USA)

Catecholamines have profound influences on cardiac function. Mechanisms relating abnormalities in sympathetic innervation to myocardial dysfunction are poorly understood, however. Recent studies have demonstrated the feasibility of noninvasively imaging the sympathetic nerves of the heart using radiolabeled MIBG. This article examines some of the experimental evidence to support the neuronal localization of MIBG. In addition, the early clinical experience is reviewed.42 references.

• OSTI ID: 6609496
• Journal Information: Journal of Thoraric Imaging; (USA), Journal Name: Journal of Thoraric Imaging; (USA) Vol. 5:3; ISSN JTIME; ISSN 0883-5993
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
AUTONOMIC NERVOUS SYSTEM
BIOLOGICAL LOCALIZATION
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DISEASES
DISTRIBUTION
DOCUMENT TYPES
DRUGS
FEASIBILITY STUDIES
HEART
IMAGE PROCESSING
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MAMMALS
MAN
MIBG
MYOCARDIAL INFARCTION
NERVOUS SYSTEM
ORGANS
PRIMATES
PROCESSING
RADIOPHARMACEUTICALS
REVIEWS
TISSUE DISTRIBUTION
VERTEBRATES