Survival of La leukemia cells following long-term exposure to /sup 60/Co gamma rays and /sup 252/Cf gamma-neutron radiation. [Mice]

Journal Article · Sat Jan 01 04:00:00 EST 1977 · Radiobiology (USSR) (Engl. Transl.); (United States)

OSTI ID:5166385

Konoplyannikov, A G; Kurpeshev, O K

Suspensions of leukemia cells from mice were exposed to applicators containing needles with /sup 252/Cf and to /sup 60/Co gamma radiation. Graphs are presented to show dose-survival curves for the irradiated cells and changes in RBE of the neutron component and mixed radiation from /sup 252/Cf with increasing doses. In view of the fact that the RBE of the neutron component is 2.2 and its contribution to the total load is 60%, over 80% of the total biological effect of mixed /sup 252/Cf radiation is referable to fast neutrons. This confirms the potential of /sup 252/Cf sources in radiation therapy of malignant neoplasms. (HLW)

• Research Organization: Scientific Research Inst. of Medical Radiology, Obninsk, USSR
• OSTI ID: 5166385
• Journal Information: Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:3; ISSN RADBA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
560162 -- Radionuclide Effects
Kinetics
& Toxicology-- Animals
Plants
Microorganisms
& Cells
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ANIMAL CELLS
ANIMALS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
COBALT 60
COBALT ISOTOPES
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
EVEN-EVEN NUCLEI
FAST NEUTRONS
FERMIONS
GAMMA RADIATION
HADRONS
HEAVY NUCLEI
HEMIC DISEASES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEUKEMIA
MAMMALS
MEDICINE
MICE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NEUTRONS
NUCLEAR MEDICINE
NUCLEI
NUCLEONS
ODD-ODD NUCLEI
RADIATION EFFECTS
RADIATION SOURCES
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RBE
RODENTS
SURVIVAL TIME
THERAPY
TUMOR CELLS
VERTEBRATES
YEARS LIVING RADIOISOTOPES