Biological effects of $sup 252$Cf neutrons

Conference · Mon Jan 01 04:00:00 EST 1973

OSTI ID:4405979

Fairchild, R G; Atkins, H L; Drew, R M; Robertson, J S

From second meeting on fundamental and practical aspects of the application of fast neutrons in clinical radiotherapy; The Hague, Netherlands (3 Oct 1973). The biological effects of /sup 252/Cf neutrons were studied with cultured cells, and with intact tissues. Measurements available to date, of the relative biological effect (RBE) and of the oxygen enhancement ratio (OER), are summarized and discussed. A table is presented to show the RBE of /sup 252/Cf neutrons, compared to /sup 137/Cs or /sup 226/Ra, for HeLa cells, hamster cells, chromosome aberrations, leukemia cells, Vicia faba, intestinal crypt cells, and mouse spleen cells, as measured by pig skin tolerance. Graphs are presented to show survival of hamster cells under oxygenated and anoxic conditions after irradiation by /sup 137/Cs and /sup 252/Cf. (HLW)

• Research Organization: Brookhaven National Lab., Upton, N.Y. (USA)
• NSA Number: NSA-29-002833
• OSTI ID: 4405979
• Report Number(s): BNL--18234; CONF-731030--1
• Country of Publication: United States
• Language: English

Related Subjects

*CALIFORNIUM 252-- NEUTRON SOURCES
*NEUTRONS-- RBE
ANIMAL CELLS
CELL CULTURES
CHROMOSOMAL ABERRATIONS
CRYPT CELLS
HAMSTERS
HELA CELLS
MICE
N48200* --Life Sciences--Radiation Effects on Cells
N48410 --Life Sciences--Radiation Effects on Plants--Basic Studies
N48520 --Life Sciences--Radiation Effects on Animals--Vertebrates
OXYGEN
SKIN
SPLEEN CELLS
SURVIVAL TIME
SWINE SPLEEN CELLS