Radiation effects on testes. XII. Monovalent electrolytes in relation to radiation injury of germinal epithelium. [Gamma radiation, rats]

Journal Article · Tue Nov 01 04:00:00 EST 1977 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3574693· OSTI ID:5143653

Gupta, G S; Bawa, S R

The effects of partial-body ..gamma.. irradiation on the content of sodium, potassium, acid deoxyribonuclease, and adenosine triphosphatase (ATPase) of rat testes were studied. It was observed that the potassium content of the testis was reduced 24 hr after irradiation and remained depressed throughout the observation period. In the case of sodium, a decrease over the first 1 to 4 days was followed by a recovery to normal level and a subsequent rise on day 6 after 2000 R. However, after 720 R, the rise in sodium could be observed as early as 24-hr postirradiation and persisted for 37 days. A maximal loss of 70 to 85% in the content of potassium per testis occurred on day 10 after 2000 R and on day 16 after 720 R. along with the changes in sodium and potassium in the testis after irradiation, there was an increase in acid deoxyribonuclease after 720 and 2000 R. ATPase was decreased up to 15 days postirradiation after exposure to 720 R. It was observed that normal testicular ATPase was stimulated by Na/sup +//K/sup +/ whereas irradiated testicular ATPase did not show such stimulation. The changes observed in testes postirradiation are presumed to be related to the degeneration of the cells of the germinal epithelium. Testosterone administration to irradiated rats tended to prevent the potassium loss but did not affect the sodium levels.

• Research Organization: Panjab Univ., Chandigarh, IN
• OSTI ID: 5143653
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 72:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METALS
ANIMALS
ATP-ASE
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DNA-ASE
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
ELEMENTS
ENZYMES
ESTERASES
GAMMA RADIATION
GONADS
HYDROLASES
INJURIES
IONIZING RADIATIONS
MALE GENITALS
MAMMALS
METALS
ORGANS
PHOSPHATASES
POTASSIUM
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RATS
RODENTS
SODIUM
TESTES
VERTEBRATES