EFFECT OF ROENTGEN RADIATION ON $beta$-GLUCURONIDASE IN RAT TESTIS

Journal Article · Mon Apr 30 04:00:00 EDT 1962 · Boll. Soc. Ital. Biol. Sper.

OSTI ID:4780962

Arata, L; Santoro, R; Severi, M A; Pecora, P

The testes were irradiated with a single 600-r dose and enzyme activity was determined in homogenates of testis, at 10-day intervals, up to the 50th postirradiation day. In comparison with the control value of 47.9 (units/mg fresh tissue), BETA -glucuronidase activity fell to 30.5 by the 10th day, then progressively rose to 78.4, 126.0, 242.0, and 275.0 in the subsequent 10-day periods. A parallel drop, followed by a rise, occurred in total activity of testis. Testicular weight fell, and seminal vesicular weight fell and then rose, during the 50-day period. Thus, the transient sterility and destruction of germinal epithelium induced by irradiation were reflected by a decrease in BETA - glucuronidase activity, whereas regeneration of this epithelium followed the rise in enzyme activity. Such parallel changes in epithelial function and enzyme activity were previously noted in vitamin E-deficient rats. (H.H.D.)

• Research Organization: Universita, Rome
• NSA Number: NSA-16-032758
• OSTI ID: 4780962
• Journal Information: Boll. Soc. Ital. Biol. Sper., Journal Name: Boll. Soc. Ital. Biol. Sper. Vol. Vol: 38
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ENZYMES
GLUCURONIDASE
GONADS
IRRADIATION
METABOLISM
QUANTITATIVE ANALYSIS
RADIATION DOSES
RATS
REGENERATION
TESTES
VARIATIONS
VITAMIN E
VITAMINS