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U.S. Department of Energy
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Studies involving the reduction of SOD-Cu/sup 2 +/ by CO/sub 2//sup -/ radicals

Conference ·
OSTI ID:5132649
Pulse radiolysis and other radiolytic techniques have proven very potent tools in the elucidation of the mechanism of O/sub 2//sup -/ dismutation by superoxide dismutases (SOD). Some recent work in this laboratory involved a systematic study of the reduction of SOD-Cu/sup 2 +/ (bovine liver) by CO/sub 2//sup -/ radicals and the kinetics of the interaction between the resultant SOD-Cu/sup +/ and peroxide, a process that is known to inactivate the enzyme and thought to generate a bound OH radical. 9 refs., 1 fig., 1 tab.
Research Organization:
Brookhaven National Lab., Upton, NY (USA)
DOE Contract Number:
AC02-76CH00016
OSTI ID:
5132649
Report Number(s):
BNL-36894; CONF-8509146-2; ON: DE86001204
Country of Publication:
United States
Language:
English